Tissue Lysates
Cayman Chemical Cholesteryl PalmItate-d9 1mg
An internal standard for the quantification of cholesteryl palmitate by GC- or LC-MS
Cayman Chemical CP 31 398hydrochlorIde 1mg
A p53 stabilizing agent; increases active mutant p53 and p53 reporter gene expression without increasing total protein levels of p53 in H1299 lung cancer cells transfected with mutant p53; is cytotoxic to a panel of 12 human glioma cell lines expressing wild-type or mutant p53 (EC50s = 11.2-22.2 μM); decreases tumor growth in an A375.S2 melanoma mouse xenograft model and completely inhibits tumor growth in a DLD-1 colon cancer mouse xenograft model at 100 mg/kg; dietary administration suppresses lung adenocarcinoma formation in a mouse model of tobacco carcinogen-induced lung adenoma and adenocarcinoma formation at 50 and 100 ppm
Cayman Chemical C24 1 dIhydro 1DeoxycRamID 1mg
A very long-chain atypical ceramide containing a 1-deoxysphinanine (m18:0) backbone; has been found as a major 1-deoxyceramide species in MEFs following application of 1-deoxysphinganine alkyne or 1-deoxysphinanine-d3
Cayman Chemical EOSd18 132 118 2 100ug
An essential ceramide for prevention of epidermal water loss; found in the outer epidermis of mammals; consecutive regio- and stereospecific oxygenation of the linoleate portion by 12(R)-LO and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss
Cayman Chemical ResolvIn E2 100ug
An SPM; inhibits increases in inflammatory exudate neutrophil infiltration in a zymosan A-induced mouse model of peritonitis; hepatic levels are increased in mice fed normal chow, as well as in a mouse model of high-fat diet-induced NAFLD, by dietary supplementation with EPA; plasma levels are increased by dietary supplementation with fish oil containing ω-3 PUFAs in patients with chronic kidney disease or peripheral artery disease